: Why is lactate dehydrogenase used to differentiate exudates from transudates? When differentiate transudates and exudates, the ration between effusion LDH and serum LDH is used: They are termed exudates if ... the pleural

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Why is lactate dehydrogenase used to differentiate exudates from transudates?
When differentiate transudates and exudates, the ration between effusion LDH and serum LDH is used:

They are termed exudates if ... the pleural fluid to serum ratio of LDH (LDHR) is > 0.6, and transudates if ... the LDHR is < 0.6. (Joseph et al, PMID 11641512)

What is the mechanism that creates this difference between transudates and exudates?

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