What's the latest application of data on the twin cycle hypothesis?
The twin cycle hypothesis states that
The accumulation of fat in liver and secondarily in the pancreas will lead to self-reinforcing cycles that interact to bring about type 2 diabetes. Fatty liver leads to impaired fasting glucose metabolism and increases export of VLDL triacylglycerol,[85] which increases fat delivery to all tissues, including the islets. The liver and pancreas cycles drive onward after diagnosis with steadily decreasing ?-cell function. However, of note, observations of the reversal of type 2 diabetes confirm that if the primary influence of positive calorie balance is removed, then the processes are reversible.
What's the current application of that data to the management of type 2 diabetes in the community?
(0)Terms of Use Privacy policy Contact About Cancellation policy © freshhoot.com2025 All Rights reserved.