: Pedigree disease risk calculation IRL - how difficult/expensive? The probability of a child being affected by genetic diseases like Spinal muscular atrophy or Canavan disease (and many other) depends solely on the parents

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Pedigree disease risk calculation IRL - how difficult/expensive?
The probability of a child being affected by genetic diseases like Spinal muscular atrophy or Canavan disease (and many other) depends solely on the parents being carriers of such disease.

Suppose we have biological materials of both parents. How difficult and how expensive (or, rather, what procedures would be involved in that, since the costs would likely vary country to country) would it be test potential parents for a large enough list of genetic diseases and calculate the probability of their offspring being affected by it?

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