Lipid test interval
What is a reasonable amount of time to wait to determine the effect of introducing a change in lipid medication (statins fenofibrate).
For example, if on January 1 one measures Triglycerides and Cholesterol are high (beyond reference range) and fenfibrate is introduced: how many days should the medication be used before re-testing to measure efficacy?
If you have experience with managing your Triglyscerides Cholesterol please state this in your response and along with any lessons-learned: thank you.
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I am not clear as to how soon an intervention results in changes but in some trials people have tested within 2 weeks.
I typically retest people at three weeks to provide reinforcement for a dietary intervention.
The quality of evidence is not really the best (taken from a management guideline) but I frankly doubt there is any better-quality evidence to answer this question:
guideline.gov/summaries/summary/48406 says,
Follow-up of People Started on Statin Treatment
Measure total cholesterol, HDL cholesterol and non-HDL cholesterol in
all people who have been started on high-intensity statin treatment at
3 months of treatment and aim for a greater than 40% reduction in
non-HDL cholesterol. If a greater than 40% reduction in non-HDL
cholesterol is not achieved:
Discuss adherence and timing of dose
Optimise adherence to diet and lifestyle measures
Consider increasing the dose if started on less than atorvastatin 80 mg and the person is judged to be at higher risk because of comorbidities, risk score or using clinical judgement. [new 2014]
Which is pretty much consistent with what I have seen and done managing patients with dislipidemia.
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