: How can 5% and 10% concentrations of benzoyl peroxide, be less effective than the 2.5%? Herbert P. Goodheart, MD 1971 (Hahnemann Medical College). Acne For Dummies (2006). p. 234. Benzoyl peroxide is the most commonly

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How can 5% and 10% concentrations of benzoyl peroxide, be less effective than the 2.5%?
Herbert P. Goodheart, MD 1971 (Hahnemann Medical College). Acne For Dummies (2006). p. 234.

Benzoyl peroxide is the most commonly used over-the-counter
acne medication, and is also the most effective medication for
treating PFB. It comes in varying strengths ranging from 2.5 to 10
percent. There’s no proof that anything higher than 2.5 percent
works any better than the higher concentration, and the lower concentrations are cheaper and may be less irritating to your skin.
Clear By Design, Clearasil, Fostex, Neutrogena, and Noxzema are
just a few of the benzoyl peroxide brand names available.

The statement beneath from this abstract feels paradoxical.

The 2.5% benzoyl peroxide formulation was more effective than its vehicle and equivalent to the 5% and 10% concentrations in reducing the number of inflammatory lesions (papules and pustules).

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