: Lithium side effects (kidney) Lithium (taken as a mood stabilizer) can lead to renal problems in patients, especially those taking it long-term. How prevalent are these side effects and how are they managed - for example,

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The Impact Of Long-Term Lithium Treatment On Renal Function In An Outpatient Population

Lithium is known to affect renal concentrating ability, and
lithium-induced polyuria is not uncommon, estimated to affect
approximately 20% of patients, but this is rarely clinically
significant. It is less clear, however, whether or not the protracted
use of lithium can cause progressive deterioration in renal function,
culminating in renal failure

How can I avoid kidney damage due to lithium?

Avoid levels of lithium that are toxic

Check blood levels of lithium to see if you are taking the lowest amount that still works for you

Check creatinine every year. Get medical help if your creatinine level stays above 1.6 mg/dl.

If possible, take lithium once a day.

Some of these are interventions that your health care provider would utilize. So make sure you follow up with your healthcare provider.
Lithium Nephropathy

Evidence of chronic renal disease is an indication for discontinuation
of the drug being administered and for consideration of alternative
medications for treatment of the patient's psychiatric disorder.

Treatments:
Polyuria --> Thiazide Diuretics & NSAIDs
Hypovolemia --> Parenteral Fluids
Dialysis may be indicated
The ICU may be indicated