: Vaccination boosters - is their precise timing important? Booster vaccines are typically booked exactly 4 weeks after the prime dose, is it known how important this specific time window is? How is vaccine efficacy changed

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Vaccination boosters - is their precise timing important?
Booster vaccines are typically booked exactly 4 weeks after the prime dose, is it known how important this specific time window is? How is vaccine efficacy changed if boosters are given later than schedule?

The vaccines I am particularly interested in are DTaP/IPV/Hib/HepB, MenB (Bexsero) and PCV (for diphteria, tetanus, pertussis, polio, haemophilus influenza type B, hepatitis B, meningococcal group B, pneumococcal infection), which are usually administrated from 8 weeks of age onward.

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