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Hoots : Does ingesting nicotinamide riboside (NR) supplements have a deleterious effect on tendons? I read on https://web.archive.org/web/20180308023625/http://www.longecity.org/forum/topic/98465-elysium-basis-trial-published-repeat-dose-nr-pterostilbene-increases - freshhoot.com

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Does ingesting nicotinamide riboside (NR) supplements have a deleterious effect on tendons?
I read on web.archive.org/web/20180308023625/http://www.longecity.org/forum/topic/98465-elysium-basis-trial-published-repeat-dose-nr-pterostilbene-increases-nad-levels-in-humans/:

As you may recall in the Personal Experiences thread here on LC a number of people (tentatively) attributed their tendonitis to taking NR [nicotinamide riboside].

Does ingesting nicotinamide riboside (NR) supplements have a deleterious effect on tendons? I'm looking for scientific studies or sound reasoning (less preferable but still could be interesting).


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There is no data to suggest that is the case.

The placebo controlled safety study www.nature.com/articles/s41514-017-0016-9 found no differences in musculoskeletal adverse side effects between active and control groups.


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