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Hoots : Less fitness for longer and healthier life It is entranced into our minds that physical training improves your fitness and health and you live longer and brighter lives. However, it is also known, though less widespread, - freshhoot.com

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Less fitness for longer and healthier life
It is entranced into our minds that physical training improves your fitness and health and you live longer and brighter lives. However, it is also known, though less widespread, that taking more calories has opposite effects, e.g. 2011 research

We are able to show that caloric restriction slows down ageing by
preventing an enzyme, peroxiredoxin, from being inactivated. This
enzyme is also extremely important in counteracting damage to our
genetic material," says Mikael Molin of the Department of Cell and
Molecular Biology.
By gradually reducing the intake of sugar and proteins, without
reducing vitamins and minerals, researchers have previously shown that
monkeys can live several years longer than expected.

This implies that we should eat less, which implies that we should have less activity (we are not talking about balanced diet rather than burning fats). What am I doing wrong? I cannot understand if I should take more activity and calories or less food and minimal activity.
I see that there is a similar question, Do fit or muscular people age better?. But, it is a bit vague (as answers confirm), and thus did not receive any consideration of the key controversy. I want sharp answer on the sharp question.


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Personally I would look at the leading causes of death in (my case) the United States:

Heart disease: 596,577
Cancer: 576,691
Chronic lower respiratory diseases: 142,943
Stroke (cerebrovascular diseases): 128,932
Accidents (unintentional injuries): 126,438
Alzheimer's disease: 84,974
Diabetes: 73,831
Influenza and Pneumonia: 53,826
Nephritis, nephrotic syndrome, and nephrosis: 45,591
Intentional self-harm (suicide): 39,518

"General old age" isn't marked up there, and although those monkeys managed to hold on to a few more years, I don't think they're plagued by the same diseases that human beings are.

This is one of those times where I think the difference between humans and apes becomes clear. Monkeys don't work office jobs, don't drive cars, don't sit on sofas, and didn't have a more than 2x increase in their life expectancy in the last two thousand years. Medical care has allowed us to far surpass our old average life expectancy of ~30 years.

I think the more important question, and it's assumptive to think the monkey-calorie study answers it, is:

Does a reduced calorie diet mean a human being will live longer, given that the leading causes of death are completely different in humans and monkeys?

You and I have a completely different set of challenges then a monkey does, so the mechanisms we need to employ for our health are likewise very different.

For all the primary causes of death except for nephritis, exercise has been shown to seriously reduce your chances of ending up with one of them (it even addresses depression which is linked to suicide).

For Alzheimer's (2010 study):

Although extensive studies are required to understand the mechanism,
it is clear that physical exercise is beneficial in the prevention of
AD and other age-associated neurodegenerative disorders.

For heart disease (2003 study):

Although the effect of an exercise program on any single risk factor
may generally be small, the effect of continued, moderate exercise on
overall cardiovascular risk, when combined with other lifestyle
modifications (such as proper nutrition, smoking cessation,and
medication use), can be dramatic.

Strokes (2004 study):

Moreover, data from studies involving stroke and able-bodied subjects
have documented the beneficial impact of regular physical activity on
multiple cardiovascular disease risk factors and provided evidence
that such benefits are likely to translate into a reduced risk for
mortality from stroke and cardiac events.

Cancers are too numerous to make sweeping statements about, but the National Cancer Institute has demonstrable evidence of exercise playing a significant role in reducing multiple cancer risks.

Diabetes is clearly reduced by nutrition and exercise, and half of "accident deaths" are from falls, many of which in the elderly although perhaps not fatal start a chain reaction of events through broken hips and then lack of physical movement. Increasing balance and coordination reduces falls, and this has been demonstrated with fitness as well (2006 study):

Power training improves balance, particularly using a low load, high
velocity regimen, in older adults with initial lower muscle power and
slower contraction.

Summary

The study on the monkeys did not show a reduction in the primary (or even secondary) causes of death in humans. As such I think it's quite a leap to think it applies to humans in any material way as the challenges to our mortality are fundamentally different than that of a monkey.


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A recent study suggests that things are more complex, and it's not clear whether caloric restriction works or doesn't work. We do know that fit people live longer and have fewer health issues. Seems like an easy decision to me.


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